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Medchemexpress LLC PIM-447 dihydrochloride | 1820565-69-2 | MFCD30489747 | 99.3% | 513.38 | C24H25Cl2F3N4O | 10 MG
Supplier: Medchemexpress LLC HY19322B10MG
PIM-447 dihydrochloride is the dihydrochloride salt of a potent, orally available pan-PIM kinase inhibitor used in preclinical research. It modulates apoptosis and JAK/STAT signaling and has been investigated for antimyeloma and bone-protective effects. This reagent is supplied for laboratory research use only.
- Potent pan-PIM kinase inhibition with low picomolar Ki values.
- Demonstrated antimyeloma and bone-protective activity in preclinical studies.
- High solubility in water and DMSO (H2O: 50 mg/mL; DMSO: ≥46.7 mg/mL).
- High purity (≈99.3%).
- Provided as a 10 mg solid suitable for preparing concentrated stock solutions.
- Stability supported by recommended storage conditions in solvent (-80°C 1 year; -20°C 6 months).
- Intended for research use only; not for human or veterinary use.
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