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Invitrogen™ Human PIM2, GST Tag Recombinant Protein

Catalog No. PV3649
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PV3649 10 μg
PR6347B 100 μg
PV4036 1 mg
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Catalog No. PV3649 Supplier Invitrogen™ Supplier No. PV3649
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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9P1W9
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 11040
Molecular Weight (g/mol) 63.7 kDa
Name Human PIM2, GST Tag
Quantity 10 μg
Regulatory Status RUO - research use only
Gene Alias DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2 h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2
Common Name PIM2
Kinase Family PIM Kinase Family
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Insect cells
Protein Family Kinases & Inhibitors
Form Liquid
Protein Subtype Serine/Threonine Kinases
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