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Selleck Chemical LLC PIM447
SDP

Catalog No. 5000000478
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PIM447 (LGH447) Hydrochloride is a novel pan-PIM kinase inhibitor with Ki values of 6 pM 18 pM 9 pM for PIM1 PIM2 PIM3 respectively It also inhibits GSK3 PKN1 and PKC but at a significantly lower potency with IC50 between 1 and 5 M ( 105-fold differential relative to the Ki on PIMs) PIM447 induces apoptosis

Catalog No. 50-000-00478 Supplier Selleck Chemical LLC Supplier No. S79855MG
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PIM447 (LGH447) Hydrochloride is a novel pan-PIM kinase inhibitor with Ki values of 6 pM 18 pM 9 pM for PIM1 PIM2 PIM3 respectively It also inhibits GSK3 PKN1 and PKC but at a significantly lower potency with IC50 between 1 and 5 M ( 105-fold differential relative to the Ki on PIMs) PIM447 induces apoptosis

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