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Selleck Chemical LLC PIM447 (LGH447) 2mg 1210608-43-7(freebase)
Supplier: Selleck Chemical LLC S79852MG
PIM447 (LGH447) is a novel pan-PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3?, PKN1, and PKC?, but at a significantly lower potency with IC50 between 1 and 5 ?M (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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