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Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 10 MG

Supplier: Medchemexpress LLC HY11161310MG
Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract. It effectively relieves pain, diarrhea, and intestinal discomfort, providing good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients.
- Inhibits GM-CSF or CXCL1/CXCL2 induced neutrophil migration and ROS production.
- Inhibits GM-CSF induced expression of cytokines (IL-1β, IL-6, and TNF-α) in primed neutrophils.
- Inhibits the contractile response to ACh or KCl in colonic circular muscle.
- Inhibits excessive systemic inflammation in Lipopolysaccharide-induced mice.
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