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Medchemexpress LLC Pinoresinol | 487-36-5 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYN62535MG

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Pinoresinol is a lignol of plant origin that serves for defense in caterpillars. It significantly sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. In vitro studies showed that Pinoresinol facilitated death-inducing signaling complex formation to trigger a caspase-8-dependent apoptotic cascade activation in TRAIL-resistant glioblastoma cells.

  • Lignol of plant origin
  • Serves for defense in caterpillars
  • Sensitizes cancer cells against TRAIL-induced apoptosis
  • Facilitates death-inducing signaling complex formation
  • Triggers caspase-8-dependent apoptotic cascade activation

Catalog No. 50-004-18010


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