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Selleck Chemical LLC Pioglitazone HCl S2046-200mg
Supplier: Selleck Chemical LLC S2046200MG
Pioglitazone HCl (AD-4833 U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes Pioglitazone HCl inhibits CYP2C8 CYP3A4 and CYP2C9 with Ki of 1 7 M 11 8 M and 32 1 M respectively Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPAR ) agonist with EC50 of 0 93 M and 0 99 M for human PPAR and mouse PPAR respectively Pioglitazone HCl inhibits mitochondrial iron uptake lipid peroxidation and subsequent ferroptosis
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