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Medchemexpress LLC Piperine | 94-62-2 | 98.99% | 285.34 | 100 G
Supplier: Medchemexpress LLC HYN0144100G
Piperine is an alkaloid isolated from pepper. It can inhibit the activity of P-glycoprotein and CYP3A4, and inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL.
- Alkaloid isolated from pepper.
- Inhibits the activity of P-glycoprotein and CYP3A4.
- Inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL.
- Shown to possess in vitro cytotoxic activity.
- Immunomodulatory, anti-oxidant, anti-asthmatic, anti-carcinogenic, anti-inflammatory, anti-ulcer, and anti-amoebic properties.
- Enhances the bioavailabilities of other drugs, including rosuvastatin, puerarin, and docetaxel (DOX) by inhibiting CYP3A and P-glycoprotein activity.
- Inhibits the phosphorylation of I-κB, p65, p38, ERK, and JNK in a dose-dependent manner, suggesting potential as an anti-inflammatory drug.
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