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Cayman Chemical PIperlongumInIn 10mg

Supplier: Cayman Chemical 900115510 MG

A dual 5-HT3 and dopamine D2 receptor antagonist (IC50s 308 and 483 nM respectively) inhibits AChE isolated from the human postmortem caudate nucleus (Kis 9.3 and 82 M for competitive and non-competitive inhibition respectively) oral administration inhibits emesis induced by cisplatin in ferrets (ED50 6170 UG/kg) and apomorphine in dogs (ED50 0.45 mg/kg) inhibits apomorphine-induced climbing and stereotypy in mice (ED50s 2.2 and 6.5 mg/kg respectively)
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