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Medchemexpress LLC Piperonylic acid | 94-53-1 | >99.9% | 166.13 | 10 G
Supplier: Medchemexpress LLC HY4140410G
Piperonylic acid is a natural molecule that closely mimics the structure of trans-cinnamic acid. It acts as a selective, mechanism-based inactivator of trans-cinnamate 4-Hydroxylase. This compound exhibits anticancer, antioxidant, and antibacterial activities.
- Has inhibitory effects on both gram-negative and gram-positive bacteria, with *S. epidermidis* being the most sensitive.
- Promotes the growth and survival of HaCaT cells and restores cell viability after UV-induced cell damage by activating the EGFR signaling pathway.
- Possesses antioxidant activity and inhibits the oxidation of β-Carotene.
- Topical application accelerates wound healing in mice by modulating inflammation and collagen deposition.
- Positively modulates EGFR expression in epidermal cells and promotes the increase of IL-10, IL-6, MCP-1, and IGF-1 expression.
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