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Apexbio Technology LLC Piriprost (potassium salt) 88851-62-1 5mg
Supplier: Apexbio Technology LLC C48285
Piriprost (potassium salt CAS 88851-62-1) also known as U 60257 is a small molecule inhibitor of leukotriene biosynthesis Leukotrienes are inflammatory mediators derived from eicosanoid metabolism in leukocytes and act via G protein-coupled receptors By inhibiting 5-lipoxygenase-mediated production of leukotriene B4 sulfidopeptide leukotrienes and the metabolite 5-HETE Piriprost reduces leukotriene-driven inflammatory processes in experimental mast cell and basophil leukemia models exhibiting IC50 values in the 9 50 M range Piriprost has also been investigated for effects on pulmonary permeability endometrial cell alkaline phosphatase activity and alveolar epithelial integrity offering utility in inflammatory and respiratory research
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