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Abcam Pitstop 2, Novel cell-permeable clathrin inhibitor, 5MG
Supplier: Abcam AB1206875MG
MW 473.4 Da, Purity >98%. Novel, selective, cell membrane permeable clathrin inhibitor. Competitively inhibits clathrin terminal domain to selectively inhibit clathrin mediated endocytosis (CME) (IC50 = 12 μM for inhibition of amphiphysin association of clathrin TD). Interferes with receptor mediated endocytosis (RME), entry of HIV and synaptic vesicle recycling.
The product is subject to the following: Abcam Restricted Use Statement
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