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Medchemexpress LLC PK11007 | 874146-69-7 | 98.7% | 100 MG
SDP

Catalog No. 5000342032
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PK11007 is a mild thiol alkylator exhibiting anticancer activity. It stabilizes p53 by selectively alkylating two surface-exposed cysteines without altering its DNA binding activity. This compound induces mutant p53 cancer cell death by elevating reactive oxygen species (ROS) levels. It is intended for research use only.

  • Causes viability reduction in mutant p53 cell lines.
  • Up-regulates protein levels of p53 target genes.
  • Increases p53 activity.
  • Increases reactive oxygen species (ROS) levels.
  • Inhibits cell proliferation and induces apoptosis.

Catalog No. 50-003-42032 Supplier Medchemexpress LLC Supplier No. HY128784100MG
May include imposed supplier surcharges.
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PK11007 is a mild thiol alkylator exhibiting anticancer activity. It stabilizes p53 by selectively alkylating two surface-exposed cysteines without altering its DNA binding activity. This compound induces mutant p53 cancer cell death by elevating reactive oxygen species (ROS) levels. It is intended for research use only.

  • Causes viability reduction in mutant p53 cell lines.
  • Up-regulates protein levels of p53 target genes.
  • Increases p53 activity.
  • Increases reactive oxygen species (ROS) levels.
  • Inhibits cell proliferation and induces apoptosis.

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