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Cayman Chemical PKC InhIbItr 5mg
Supplier: Cayman Chemical 354945 MG
A PKCβ Inhibitor (IC50s = 21 and 5 nM, respectively); selective for PKCβ1 and PKCβ2 over PKCα, PKCε, and PKCγ (IC50s = 331, 2,807, and >1,000 nM, respectively), as well as JAK1, JAK2, and TYK2 (IC50s = 770, 3,850, and 2,310 nM, respectively); inhibits JAK3 (IC50 = 17 nM); induces apoptosis and inhibits cell cycle progression in 2F7 AIDS-related Burkitt's lymphoma cells at 14 µM
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