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Apexbio Technology LLC PKI 14-22 amide, myristoylated 201422-03-9 1mg
SDP

Catalog No. 5000089632
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PKI 14-22 amide myristoylated (CAS 201422-03-9) is a cell-permeable inhibitor of cAMP-dependent protein kinase (PKA) By competitively blocking PKA activity this peptide fragment interferes with the phosphorylation of serine/threonine residues on protein substrates thereby modulating downstream signaling pathways involved in gene expression apoptosis differentiation and cell proliferation In cellular models myristoylated PKI 14-22 amide inhibits PKA-mediated processes such as 8-bromo-cAMP-induced hyperalgesia and IgG-Fc receptor stimulated phagocytosis in neutrophils in a dose-dependent manner This compound serves as a valuable research tool for dissecting PKA function and exploring PKA-related pathophysiology including cancer and immune regulation

Catalog No. 50-000-89632 Supplier Apexbio Technology LLC Supplier No. B90091
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PKI 14-22 amide myristoylated (CAS 201422-03-9) is a cell-permeable inhibitor of cAMP-dependent protein kinase (PKA) By competitively blocking PKA activity this peptide fragment interferes with the phosphorylation of serine/threonine residues on protein substrates thereby modulating downstream signaling pathways involved in gene expression apoptosis differentiation and cell proliferation In cellular models myristoylated PKI 14-22 amide inhibits PKA-mediated processes such as 8-bromo-cAMP-induced hyperalgesia and IgG-Fc receptor stimulated phagocytosis in neutrophils in a dose-dependent manner This compound serves as a valuable research tool for dissecting PKA function and exploring PKA-related pathophysiology including cancer and immune regulation

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