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Medchemexpress LLC PKI-179 hydrochloride | 1463510-35-1 | 99.7% | 525.00 | 10 MG
Supplier: Medchemexpress LLC HY11080A100MG
PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor. It exhibits inhibitory activity against PI3K-α, PI3K-β, PI3K-γ, PI3K-δ, and mTOR, with varying IC50 values. This compound also shows activity against E545K and H1047R mutations and demonstrates anti-tumor effects in vivo.
- Potent and orally active.
- Dual PI3K/mTOR inhibitor.
- Inhibits PI3K-α, PI3K-β, PI3K-γ, PI3K-δ, and mTOR.
- Active against E545K and H1047R.
- Shows anti-tumor activity in vivo.
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