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Medchemexpress LLC PKUMDL-LC-101-D04 100mg | 2143896-83-5 | 378.9 | C14H22N4O2S2 · HCl | 100 MG
Supplier: Medchemexpress LLC HY115627100MG
PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used in research to modulate ferroptosis and lipid-peroxide-mediated cell death. It increases GPX4 enzymatic activity in biochemical assays and has demonstrated activity in cell extracts and cellular protection assays.
- Allosteric activator of glutathione peroxidase 4.
- Increases GPX4 activity to about 150% in a cell-free assay at 20 μM.
- Restores GPX4 activity in cell extracts at 61 μM.
- Reduces cholesterol hydroperoxide-induced cell death in mouse embryonic fibroblasts.
- High purity research-grade material suitable for biochemical and cellular assays.
- Molecular weight 378.9 and formula C14H22N4O2S2 · HCl.
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