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Medchemexpress LLC PKUMDL-LC-101-D04 500mg | 2143896-83-5 | 378.93 g·mol⁻¹ | C14H23ClN4O2S2 | 500 MG
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Supplier:  Medchemexpress LLC HY115627500MG

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PKUMDL-LC-101-D04 is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used in research on ferroptosis, lipid peroxidation, and inflammation. It increases GPX4 enzymatic activity in cell-free and cellular assays (reported pEC50 = 4.7) and protects cells from cholesterol peroxide-induced toxicity.

  • Allosteric activator of GPX4, reported pEC50 = 4.7.
  • Increases GPX4 activity to ~150% in cell-free and cellular extracts at reported concentrations.
  • Demonstrated inhibition of ferroptosis and protection against lipid peroxide-induced cell death.
  • Molecular weight ~378.93 g·mol⁻¹ and chemical formula C14H23ClN4O2S2.
  • Supplied as a high-purity research chemical suitable for biochemical and cellular assays.

Catalog No. 50-002-26656


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