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Medchemexpress LLC Plecanatide acetate | 1075732-84-1 | 99.5% | 1741.94 | 1 ML
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Supplier:  Medchemexpress LLC HY108741A1MG

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Plecanatide acetate, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. It activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. It can be used for the research of chronic idiopathic constipation and also shows anti-inflammatory activity in models of murine colitis.

  • Orally active guanylate cyclase-C (GC-C) receptor agonist.
  • Activates GC-C receptors to stimulate cGMP synthesis.
  • Potential for research in chronic idiopathic constipation.
  • Shows anti-inflammatory activity in models of murine colitis.

Catalog No. 50-003-46449


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