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Cayman Chemical Plerixafor hydrochloride hyd
SDP

Supplier:  Cayman Chemical 100113321 MG

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An antagonist of CXCR4 (IC50s = 0.02-0.13 UG/ml); selective for CXCR4 over CXCR1-3 and CXCR5-9 (IC50s = >25 UG/ml); decreases infectious virus content in the supernatant of Jurkat cells chronically infected with HIV-1(IIIB) (EC50 = ~0.02 UG/ml); mobilizes murine and human hematopoietic stem and murine long-term repopulating cells for transplantation; increases T cell trafficking in mouse blood, spleen, and central nervous system; decreases the number of 4T1 murine mammary carcinoma cells in the lung in a mouse model of lung metastasis at 1.25 mg/kg twice per day

Catalog No. 50-288-7129


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