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Apexbio Technology LLC PLP (139-151) 122018-58-0 5mg
Supplier: Apexbio Technology LLC B53155
PLP 139-151 is a peptide derived from proteolipid protein (PLP) a major component of myelin in the central nervous system It is designed to trigger the proliferation and activation of CD4 T cells specific to myelin antigens thereby initiating autoimmune responses against neural tissues PLP 139-151 exerts its biological activity primarily through the induction of T cell-mediated immune responses In experimental autoimmune encephalomyelitis (EAE) models PLP 139-151 demonstrates immunodominant activity by facilitating disease induction Based on these pharmacological properties PLP 139-151 holds research potential in studies of T cell-mediated immune events autoimmune inflammation and the evaluation of therapeutic strategies targeting immune modulation and tolerance induction in neuroimmunological diseases
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