Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000386491

Medchemexpress LLC PLpro inhibitor | 1093070-14-4 | 99.9% | 346.42 | 10 MM 1 ML
SDP

Supplier:  Medchemexpress LLC HY1754210MM/1ML

Encompass_Preferred

PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC50 of 2.6 μM. It inhibits SARS-CoV-2 PLpro with an IC50 of 5.0 μM and an EC50 of 21.0 μM. It is a noncovalent inhibitor that blocks SARS virus replication and shows significant antiviral activity with EC50 values of 13.1 μM without toxicity up to the highest concentration tested. The increasing antiviral potency correlates with the in vitro inhibition of PLpro, suggesting a direct action on the enzyme in cells.

  • Potent inhibitor of papain-like protease (PLpro) (IC50 = 2.6 μM).
  • Inhibits SARS-CoV-2 PLpro (IC50 = 5.0 μM, EC50 = 21.0 μM).
  • Displays significant antiviral activity (EC50 = 13.1 μM) without toxicity.
  • Noncovalent class of inhibitor that blocks SARS virus replication.

Catalog No. 50-003-86491


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.