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Cayman Chemical Plumula nlumbns nfern 50mg
Supplier: Cayman Chemical 3475350 MG
An alkaloid with diverse biological activities; inhibits ADP-, collagen-, thrombin-, U46619-, or adrenaline-induced aggregation of isolated human platelets at 3 µM; prevents LPS- and ATP-induced pyroptosis, NLRP3 inflammasome activation, and the production of ROS in HUVECs at 2 µM; decreases expression of the genes encoding PPARγ, C/EBPα, SREBP-1c, and FASN and reduces lipid accumulation in 3T3-L1 cells; enhances TRAIL-induced LC3-II accumulation and cell death in DU145 prostate cancer cells; improves reference and working memory, as well as reduces hippocampal lipid peroxidation and IL-6, IL-1β, and TNF-α levels, in a rat model of aluminum chloride-induced Alzheimer’s disease at 25 and 50 mg/kg
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