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STEMCELL Technologies PluriSIn-1, Size: 10 mg

Supplier: STEMCELL Technologies 72822
PluriSIn-1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (Ben-David et al.).DIFFERENTIATION· Selectively eliminates undifferentiated human embryonic stem (ES) and induced pluripotent stem (iPS) cells while sparing differentiated cells, and prevents teratoma formation in transplanted mice (Ben-David et al.).· Induces apoptosis of Nanog-positive iPS cells in vitro, while leaving iPS cell-derived cardiomyocytes unaffected (Zhang et al.).
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