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Medchemexpress LLC pm26TGF-β1 peptide TFA | 99.7% | 1506.58 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP2294A5MG

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pm26TGF-β1 TFA peptide mimics a portion of the human TGF-β1 molecule. It exhibits high affinity for the TGF-β1 receptor and possesses potent anti-inflammatory properties without inducing neutrophils' chemoattraction.

  • Significantly down-modulates TNF-α and up-regulates IL-10 responses in peripheral blood mononuclear cells (PBMC) at concentrations of 1 μM, 10 μM, and 100 μM over 24-48 hours.
  • Leads to regulatory T cells (Treg) phenotype differentiation.
  • Decreases neutrophil migration during inflammatory processes in male C57BL/6 mice when administered via subcutaneous injection at doses of 100-1000 μg/kg.

Catalog No. 50-004-22110


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