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Enzo Life Sciences Phenylmethylsulfonyl fluoride (25g). CAS: 329-98-6
Supplier: Enzo Life Sciences ALX270184G025
Irreversible inhibitor of serine proteases. Widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity. Spleen membranes used for CB2 studies do not require this pretreatment, as FAAH activity is absent in these cells. Inhibits also cysteine proteases like papain (reversible by DTT treatment, ALX-280-001), as well as internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor see AEBSF (ALX-270-022). Alternative name: PMSF, Benzylsulfonyl fluoride. Formula: C7H7FO2S. MW: 174.2. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol, methanol or isopropanol; insoluble in water. Long Term Storage: Ambient.
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