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Medchemexpress LLC PMX 205 Trifluoroacetate | 99.5% | 953.06 | 100 MG
Supplier: Medchemexpress LLC HY110136A100MG
PMX 205 Trifluoroacetate is identified as a specific complement C5aR1 isoform antagonist. It is intended for research use only and is not sold to patients.
- Specific complement C5aR1 isoform antagonist.
- Orally active, selective C5aR antagonist.
- Extends survival time and reduces end-stage motor scores in SOD1G93A rats.
- Reduces astroglial proliferation in the lumbar spinal cord.
- Decreases fibrillar plaque load in Tg2576 mice.
- Significantly reduces hyperphosphorylated tau in 3xTg mice.
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