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Tocris Bioscience™ PMX 53
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Catalog No. 54731
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54-731 1 mg
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Catalog No. 54-731 Supplier Tocris Bioscience™ Supplier No. 5473/1
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Description

Potent C5a receptor antagonist

PMX 53 is a potent C5a receptor antagonist (IC50 = 20 nM). Also MrgX2 agonist. Stimulates MrgX2-mediated mast cell degranulation. Also inhibits C5a-induced hypernociception in rats, inhibits lung metastasis in a mouse breast cancer model and reduces atherosclerotic lesions in a mouse model of atherosclerosis.

Negative Control also available.

Specifications

Purity 0.95
Description PMX 53
Molecular Weight (g/mol) 896.1
Product Type PMX 53
Quantity 1 mg
Sequence Ac-Phe-cyclo(Orn-Pro-dCha-Trp-Arg)

For Research Use Only

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