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Medchemexpress LLC PNC-27 acetate | 99.9% | 4031.73 | 50 MG
Supplier: Medchemexpress LLC HYP3508A50MG
PNC-27 acetate is a chimeric p53-penetratin peptide that binds to HDM-2 in a p53 peptide-like structure. It induces selective membrane-pore formation and leads to cancer cell lysis. PNC-27 acetate is an anticancer peptide and can be used in acute myeloid leukemia research.
- Induces cancer cell death.
- Binds to cell membrane-bound HDM-2 in A2058 and MCF-7 cells.
- Shows anti-leukemia activity in mice.
- Reduces AML engraftment and prolongs survival in AML mice.
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