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Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | 537.96 | 25 MG
Supplier: Medchemexpress LLC 25MGHY13917A
PND-1186 hydrochloride is a potent, highly-specific, and reversible inhibitor of FAK with an IC50 of 1.5 nM. It selectively promotes tumor cell apoptosis.
- Potent, highly-specific, and reversible inhibitor of FAK
- Selectively promotes tumor cell apoptosis
- Inhibits FAK Tyr-397 phosphorylation
- Elevates total FAK protein levels
- Inhibits 4T1 subcutaneous tumor growth
- Induces apoptosis in BALB/c mice
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