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Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11766450MG

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PNR-7-02 is a small-molecule research inhibitor of DNA polymerase eta (Pol η). It is an indole thio-barbituric acid derivative reported to inhibit Pol η (IC50 ≈ 8 μM), with activity against hRev1 and DNA polymerase λ, and reported synergy with cisplatin in certain cancer cell lines.

  • Purity 98.0%.
  • Molecular weight 445.92.
  • Chemical formula C24H16ClN3O2S.
  • Appearance solid.
  • Recommended solvent DMSO; solubility note: 1 mg/mL, ultrasonic and warming, heat to 60°C.
  • Storage powder: -20°C for 3 years; in solvent: -80°C for 6 months.

Catalog No. 50-002-26243


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