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AdipoGen Podoplanin ms mAb RTD4E10
SDP

Supplier:  AdipoGen AG20T0101C100

Encompass_Preferred

Monoclonal Antibody. Recognizes mouse podoplanin. Does not cross-react with human podoplanin. Isotype Hamster IgG. Clone RTD4E10. Applications ELISA, IHC, IP, WB. Lyophilized. Podoplanin is expressed on glomerular epithelial cells podocytes, type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 CLEC-2. Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Catalog No. 50-256-3358


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