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Sigma Aldrich Poly(ethylene glycol)-block-polyethyleneimine

Catalog No. 910791500MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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91-079-1500MG 500 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Gene therapy using polymeric nonviral vectors promises considerable advances in the treatment of many genetic and acquired diseases due to the carrier safety and low immunogenicity profiles. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

Specifications

Linear Formula CH3(C2H4O)m(C2H5N)nOH
Quantity 500 mg
Synonym Linear poly(ethylene glycol)-block-polyethylenimine; PEG-b-PEI; PEG-PEI
Molecular Weight (g/mol) 10000
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