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Cell Signaling TechnologySupplier Diversity Partner TLE1/2/3/4 Antibody 100 ul DFS Item

Manufacturer:  Cell Signaling TechnologySupplier Diversity Partner 4681S

4681S , Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho (1). TLEs contain several WD-repeats implicated in protein-protein interaction (2,3). TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3 (4-7). TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions (8).

Catalog No. 50-195-337

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