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Sigma Aldrich Polyester Bis-mpa Dendron 2 Carboxyl 1 Biotin (core) Generation 1

Catalog No. 91127550MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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91-127-550MG 50 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

  • Polymer architecture: Dendron
  • End Group Functionality: Boc-protected amine
  • Boc: tert-Butyloxycarbonyl
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid. Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers.
  • Dendrons synthesized from bis-MPA are biodegradable and exhibit low cytotoxicity, making them well-suited for use in biological research applications. These materials have been utilized in various applications, including signal amplification in bioassays and drug delivery. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications. Additionally, the azide-core can be readily conjugated using either copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC).

Specifications

Molecular Formula C31H48N2O16S
Linear Formula C31H48N2O16S
Quantity 50 mg
Synonym Bis-MPA dendron; PFd-G1-Biotin-COOH
Molecular Weight (g/mol) 736.78
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