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Medchemexpress LLC Polygalasaponin F | 882664-74-6 | 1091.24 | 10 MG
SDP

Supplier:  Medchemexpress LLC HYN039210MM/1ML

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Polygalasaponin F is an orally active triterpenoid saponin monomer with broad biological activity, modulating several key cellular pathways.

  • Downregulates Bax, p53, caspase-3, NF-κB p65, and MEK1.
  • Restores and upregulates Bcl-2.
  • Activates PI3K/Akt signaling pathway.
  • Inhibits p38 MAPK phosphorylation, NF-κB translocation, TLR4-mediated signaling, mitophagy, and ROS production.
  • Enhances cell viability, suppresses apoptosis, and maintains mitochondrial function.
  • Alleviates Ca2+ overload and inhibits inflammatory cytokine release.
  • Alleviates lung injury induced by influenza A H1N1.
  • Alleviates cerebral ischemia-reperfusion injury.
  • Applicable for research in neurodegenerative diseases and infectious diseases.

Catalog No. 50-003-89290


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