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Sigma Aldrich Fine Chemicals Biosciences Polyinosinic–polycytidylic acid sodium salt, 42424-50-0, MFCD00131984, 100 mg
Supplier: Sigma Aldrich Fine Chemicals Biosciences P1530100MG
TLR ligand tested, Synonym: Poly (I:C), Poly(I) • Poly. TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid (Poly(I) • Poly(C)) is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
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