Polysorbate 20, MP Biomedicals™

Description

Derived from sorbitan ester. Polysorbate 20, MP Biomedicals is a nonionic surfactant that is soluble/dispersable in water. It is typically used for the preparation of stable oil-in-water emulsions, particularly in pharmaceutical applications.

Used as oil-in-water emulsifiers in pharmaceuticals, cosmetics, cleaning compounds, etc. It has been used in pre-extraction of membranes to remove peripheral proteins. It has been used as a blocking agent on nitrocellulose.

Specifications

Chemical Identifiers

• CAS: 9005-64-5
• Molecular Formula: (C2H4O)y(C2H4O)w(C2H4O)x(C2H4O)zC18H34O6
• Molecular Weight (g/mol): 522.68
• MDL Number: MFCD00165986
• InChI Key: HMFKFHLTUCJZJO-UHFFFAOYNA-N
• Synonym: Polysorbate 20, Polyoxyethylene (20) Sorbitan Monolaurate, Glycosperse L-20X, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate, TWEEN™, 20, PEG(20)sorbitan monolaurate
• PubChem CID: 443314
• IUPAC Name: 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
• SMILES: CCCCCCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO

• Physical Form: Liquid
• Boiling Point: >100°C (literature)
• Density: 1.095g/mL (Lit.)
• Concentration: Working Concentration: As a blocking agent on nitrocellulose at a typical concentration of 0.05%. Used at concentration of 2% for extraction of membrane-bound proteins.
• pH: 5 to 7 (1% aq. soln.) (literature)
• Quantity: 1 L
• Refractive Index: n20/D 1.468 (Lit.)
• Specific Gravity: 1.08-1.13
• Viscosity: 400 cps at 25°C (Lit.)
• Solubility Information: Soluble/miscible in water (1g/20 mL) to give a clear yellow solution; miscible with alcohol, dioxane, and ethyl acetate; practically insoluble in liquid paraffin and fixed oils (such as mineral oil).
• Formula Weight: 1228
• Concentration or Composition (by Analyte or Components): 0.06mM

Safety and Handling

Recommended Storage

Store at Room Temperature (15-30°C).