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Apexbio Technology LLC POM 1,50mg CAS# 12141-67-2

Supplier: Apexbio Technology LLC B715350

POM 1, also known as sodium polyoxotungstate and sodium metatungstate, is a novel, potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolases (Ecto-NTPDases). POM 1 exhibits minor selectivity for NTPDase 1 and NTPDase 3 over NTPDase 2, with Ki values being 2.58, 28.8 and 3.26 μM for NTPDase 1 (CD39), NTPDase 2 and NTPDase 3, respectively. Ecto-NTPDases capable of hydrolyzing nucleoside tri- and diphosphates are able to reduce the effective concentration of the released nucleotide, and inhibitors of Ecto-NTPDases can thus serve as valuable tools for amplifying the biological effects triggered by extracellularly released nucleotides. Other sizes are also available. Please inqury us for quote.
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