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Medchemexpress LLC Pomalidomide 4'-alkylC5-acid | 2225940-49-6 | 98.8% | 250 MG
Supplier: Medchemexpress LLC 250MGHY130737
Pomalidomide 4'-alkylC5-acid is an E3 ligase ligand-linker conjugate. It contains a cereblon (CRBN) ligand, which is Pomalidomide based, and a linker. This compound can be utilized in the synthesis of PROTAC (Proteolysis Targeting Chimeras). PROTACs are composed of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. These molecules function by harnessing the intracellular ubiquitin-proteasome system to achieve the selective degradation of target proteins.
- Can be utilized in the synthesis of PROTAC
- Contains a cereblon (CRBN) ligand
- Contains a linker
- Targets an E3 ubiquitin ligase
- Targets the protein of interest
- Harnesses the intracellular ubiquitin-proteasome system
- Achieves selective degradation of target proteins
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