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Medchemexpress LLC Pomalidomide 4'-PEG3-azide | 2271036-46-3 | 96.3% | 100 MG
Supplier: Medchemexpress LLC HY130652100MG
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates a Pomalidomide-based cereblon ligand and a linker. It is used for the synthesis of iRucaparib-TP3, a highly efficient PARP1 degrader developed using the PROTAC approach. This compound is also a click chemistry reagent containing an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- E3 ligase ligand-linker conjugate
- Incorporates a Pomalidomide-based cereblon ligand
- Utilized for synthesis of iRucaparib-TP3
- Highly efficient PARP1 degrader
- Click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reactions
- Enables strain-promoted alkyne-azide cycloaddition reactions
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