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Medchemexpress LLC Pomalidomide-amino-PEG4-NH2 hydrochloride | 2331259-45-9 | >99.3% | 542.97 | 50 MG
Supplier: Medchemexpress LLC HY138859A50MG
Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. This compound incorporates the Pomalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. PROTACs, or Proteolysis-targeting chimeras, are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system through two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting the protein of interest.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Used in PROTAC technology
- Target: E3 ligase ligand-linker conjugates
- Pathway: PROTAC
- Target: Cereblon
- Soluble in DMSO (250 mg/mL)
- Soluble in various in vivo solvent systems (≥ 6.25 mg/mL)
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