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Medchemexpress LLC Pomalidomide-PEG2-azide | 2267306-14-7 | MFCD32198604 | 96.6% | 444.40 g/mol | C19H20N6O7 | 5 MG
Supplier: Medchemexpress LLC HY1375375MG
Pomalidomide-PEG2-azide is a pomalidomide-based cereblon (CRBN) ligand-linker conjugate featuring a two-unit polyethylene glycol spacer and an azide functional group. It is developed as a building block for targeted protein degrader (PROTAC) research and for modular conjugation via click chemistry, offering a balance of solubility and reactivity for medicinal chemistry applications.
- Provides a pomalidomide scaffold for CRBN recruitment.
- Two-unit PEG linker improves solubility and linker flexibility.
- Azide handle enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Suitable for use as a PROTAC building block and linker module.
- Available in small-scale quantities for medicinal chemistry and assay development.
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