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Medchemexpress LLC Pomalidomide-PEG3-azide | 2267306-15-8 | MFCD32198606 | 98.9% | 488.45 | C21H24N6O8 | 5 MG
Supplier: Medchemexpress LLC HY1375385MG
Pomalidomide-PEG3-azide is an E3 ligase ligand-linker conjugate that combines a pomalidomide-derived cereblon ligand with a three-unit polyethylene glycol linker terminated in an azide. It is intended for use in targeted protein degradation workflows and for click-chemistry functionalization to attach pomalidomide-based ligands to alkyne- or strained-alkyne-containing molecules.
- Facilitates PROTAC construction via CRBN-mediated recruitment of E3 ligase.
- Azide terminus enables copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- PEG3 linker provides flexible spacing between ligand and cargo.
- High reported purity (≈98.9%) supports analytical and synthetic applications.
- Soluble in DMSO at high concentration; store under inert atmosphere at -20°C to preserve stability.
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