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Apexbio Technology LLC β-Pompilidotoxin 216064-36-7 10mg
Supplier: Apexbio Technology LLC A113210
-Pompilidotoxin ( -PMTX CAS 216064-36-7) is a peptide neurotoxin isolated from the venom of the solitary wasp Batozonellus maculifrons Composed of 13 amino acids (C71H124N22O17) -PMTX modulates neuronal excitability by selectively slowing the inactivation of voltage-gated sodium (Na ) channels without affecting cardiac Na channels This action is thought to involve interaction with neurotoxin receptor site 3 on the extracellular surface of neuronal Na channels Compared to -pompilidotoxin -PMTX exhibits greater potency in enhancing synaptic transmission at neuromuscular junctions -PMTX serves as a valuable tool for investigating Na channel kinetics and the molecular mechanisms regulating synaptic transmission
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