Medchemexpress LLC Ponatinib hydrochloride | 1114544-31-8 | 99.8% | 569.02 | 25 MG

Supplier:  Medchemexpress LLC 25MGHY108766

Ponatinib hydrochloride, also known as AP24534 hydrochloride, is an orally active multi-targeted kinase inhibitor. It inhibits various kinases with IC50s including 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src.

• Purity of 99.76%
• CAS number: 1114544-31-8
• Molecular weight: 569.02
• Appears as an off-white to light yellow solid
• Soluble in DMSO at 25 mg/mL
• Targets Bcr-Abl, FGFR, PDGFR, VEGFR, Src, and Autophagy pathways
• Store at 4°C, sealed, away from moisture; in solvent, store at -80°C for 6 months or -20°C for 1 month

Catalog No. 50-003-47270