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Medchemexpress LLC Poneratoxin acetate | 137084-94-7 | 2756.35 (free base) | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP10234A5MG

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Poneratoxin acetate is the acetate salt form of Poneratoxin. It functions as a neurotoxic peptide and modulator for voltage-gated sodium channels (NaV), particularly NaV1.6 and NaV1.7. This compound lowers the voltage threshold for activation, inhibits the inactivation of channels, and enhances neuronal excitability, contributing to the transmission of pain signals.

  • Acts as a modulator for voltage-gated sodium channels (NaV)
  • EC50 values of 97 nM for NaV1.6 and 2.3 μM for NaV1.7
  • Lowers the voltage threshold for activation
  • Inhibits the inactivation of channels
  • Enhances the excitability of neurons
  • Leads to the transmission of pain signals
  • Solid with a white color
  • For research use only

Catalog No. 50-004-25457


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