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Medchemexpress LLC Poricoic acid A | 137551-38-3 | 1 MG
SDP

Catalog No. 5000421275
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Poricoic acid A is an orally active anti-tumor agent isolated from Poria cocos. It enhances melatonin inhibition of AKI-to-CKD transition by regulating the Gas6/AxlNFκB/Nrf2 axis and attenuates fibroblast activation and abnormal extracellular matrix remodeling in renal fibrosis by activating AMPK and inhibiting Smad3. When combined with Melatonin, it significantly reduces the rise in serum creatinine and urea levels in a rat model.

  • Isolated from Poria cocos
  • Orally active anti-tumor agent
  • Enhances melatonin inhibition of AKI-to-CKD transition
  • Attenuates fibroblast activation and abnormal extracellular matrix remodeling
  • Activates AMPK and inhibits Smad3
  • Reduces serum creatinine and urea levels in rat models
  • Ameliorates renal fibrosis and podocyte injury
  • Attenuates oxidative stress and inflammation

Catalog No. 50-004-21275 Supplier Medchemexpress LLC Supplier No. HYN29951MG
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Poricoic acid A is an orally active anti-tumor agent isolated from Poria cocos. It enhances melatonin inhibition of AKI-to-CKD transition by regulating the Gas6/AxlNFκB/Nrf2 axis and attenuates fibroblast activation and abnormal extracellular matrix remodeling in renal fibrosis by activating AMPK and inhibiting Smad3. When combined with Melatonin, it significantly reduces the rise in serum creatinine and urea levels in a rat model.

  • Isolated from Poria cocos
  • Orally active anti-tumor agent
  • Enhances melatonin inhibition of AKI-to-CKD transition
  • Attenuates fibroblast activation and abnormal extracellular matrix remodeling
  • Activates AMPK and inhibits Smad3
  • Reduces serum creatinine and urea levels in rat models
  • Ameliorates renal fibrosis and podocyte injury
  • Attenuates oxidative stress and inflammation

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