Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ POROS™ MabCapture™ A/G Select Resin

Manufacturer:  Thermo Scientific™ 82087

 View more versions of this product

Catalog No. PI82087


Add to cart

Description

Description

  • Maintain high dynamic binding capacity at linear flow rates over 700 cm/hr
  • Design processes with greater flexibility (shorter bed heights, faster flow rates, or both) due to the improvements made to the antibody binding efficiency
  • Obtain the highest dynamic binding capacity for antibodies vs. conventional agarose- or silica-based Protein A or Protein G resins
  • Purify polyclonal IgG from nearly any mammalian species
  • Sanitize and depyrogenate with standard agents used for other chromatography products
  • Recognize major increases to process productivity and reduce the downstream bottleneck

Protein A/G is a chimeric genetically-engineered protein that combines the five IgG binding domains of Protein A and two IgG binding domains of Protein G. Protein A/G is not as pH-dependent as Protein A alone, but otherwise has the additive properties of Protein A and G. Protein A/G binds nearly all isotypes and mammalian species of IgG from serum, ascites fluid, cell culture supernatant and other antibody samples, thereby enabling effective antibody purification.

The development of humanized monoclonal antibodies has continued to fuel the growth of the biotherapeutic market. Addressing the therapeutic demand for monoclonal antibodies has led to major improvements to the cell-based expression systems that are used to manufacture these proteins. Consequently, these improvements have moved the processing bottleneck from upstream cell expression to downstream purification. POROS MabCapture A/G Select chromatography resin offers the capacity, efficiency, and flexibility needed to make improvements to the downstream purification platform, resulting in major increases to process productivity and antibody manufacturing.

Specifications

Specifications

Store in refrigerator (2–8°C).
POROS™
Wet Ice
Poros Bead
IgG Antibodies, Ig Antibodies
Protein A/G
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit