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Apexbio Technology LLC Posaconazole 171228-49-2 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A17185.1

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Posaconazole a triazole antifungal derivative of itraconazole acts by inhibition of sterol 14 -demethylase involved in fungal ergosterol biosynthesis It binds directly to the enzyme s heme cofactor blocking conversion of lanosterol into downstream sterol intermediates disrupting fungal membrane integrity and cellular function Posaconazole shows inhibitory activity in vitro against Candida albicans strains (IC50 0 007 0 3 g/ml) and Aspergillus species including A fumigatus and A flavus (IC50 0 03 g/ml) It is commonly utilized in biomedical research investigating fungal biology and drug resistance mechanisms

Catalog No. 50-000-63045


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